At least 22 civilians, including 10 children, were killed in an air strike carried out by unidentified aircraft at a village held by the so-called Islamic State group in eastern Syria, a monitor said on Wednesday.

The Syrian Observatory for Human Rights said the civilians were from two families at Hojna in Deir Ezzor, which borders Iraq and is the country’s second biggest province after Homs.

The village is located in the oil-rich province of Deir Ezzor which is mostly under the control of IS and has been regularly targeted by a US-led military coalition.

The only part of the eastern province outside of IS control is its capital, which is also named Deir Ezzor and is held by forces loyal to Syrian President Bashar al-Assad.

So-called IS has carried out a series of attacks across Europe and has been targeted by military offensives on several fronts in Syria and Iraq, where it declared an Islamic “caliphate” in 2014.

So-called IS is targeted by warplanes of the US-led coalition in Syria, as well as Turkey, the Syrian regime and its ally Russia in the northern province of Aleppo, Deir Ezzor and its stronghold of Raqa.